Cancer Immunology Recent Publications

2024

Multicenter prospective blinded melanoma detection study with a handheld elastic scattering spectroscopy device.Hartman RI, Trepanowski N, Chang MS, Tepedino K, Gianacas C, McNiff JM, Fung M, Braghiroli NF, Grant-Kels JM. JAAD Int. 2024 Jun; 2023 Nov 15. PMID: 38371666.
Proof-of-concept studies with a computationally designed M(pro) inhibitor as a synergistic combination regimen alternative to Paxlovid.Papini C, Ullah I, Ranjan AP, Zhang S, Wu Q, Spasov KA, Zhang C, Mothes W, Crawford JM, Lindenbach BD, Uchil PD, Kumar P, Jorgensen WL, Anderson KS. Proc Natl Acad Sci U S A. 2024 Apr 23; 2024 Apr 15. PMID: 38621119.
IL-1 receptor 1 signaling shapes the development of viral antigen-specific CD4(+) T cell responses following COVID-19 mRNA vaccination.Park HJ, Shin MS, Shin JJ, Kim H, Kang B, Par-Young J, Unlu S, Afinogenova Y, Catanzaro J, Young J, Kim M, Lee SJ, Jeon S, You S, Racke MK, Bucala R, Kang I. EBioMedicine. 2024 Apr 18; 2024 Apr 18. PMID: 38640835.
Vascular mimicry as a facilitator of melanoma brain metastasis.Provance OK, Oria VO, Tran TT, Caulfield JI, Zito CR, Aguirre-Ducler A, Schalper KA, Kluger HM, Jilaveanu LB. Cell Mol Life Sci. 2024 Apr 18; 2024 Apr 18. PMID: 38635031.
Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology.Phan HV, Tsitsiklis A, Maguire CP, Haddad EK, Becker PM, Kim-Schulze S, Lee B, Chen J, Hoch A, Pickering H, van Zalm P, Altman MC, Augustine AD, Calfee CS, Bosinger S, Cairns CB, Eckalbar W, Guan L, Jayavelu ND, Kleinstein SH, Krammer F, Maecker HT, Ozonoff A, Peters B, Rouphael N, Montgomery RR, Reed E, Schaenman J, Steen H, Levy O, Diray-Arce J, Langelier CR. Sci Transl Med. 2024 Apr 17; 2024 Apr 17. PMID: 38630846.
Highly Reactive Group I Introns Ubiquitous in Pathogenic Fungi.Liu T, Pyle AM. J Mol Biol. 2024 Apr 15; 2024 Mar 5. PMID: 38447889.
A supervised bayesian factor model for the identification of multi-omics signatures.Gygi JP, Konstorum A, Pawar S, Aron E, Kleinstein SH, Guan L. Bioinformatics. 2024 Apr 11; 2024 Apr 11. PMID: 38603606.
Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease.Zhou X, Shen X, Johnson JS, Spakowicz DJ, Agnello M, Zhou W, Avina M, Honkala A, Chleilat F, Chen SJ, Cha K, Leopold S, Zhu C, Chen L, Lyu L, Hornburg D, Wu S, Zhang X, Jiang C, Jiang L, Jiang L, Jian R, Brooks AW, Wang M, Contrepois K, Gao P, Rose SMS, Tran TDB, Nguyen H, Celli A, Hong BY, Bautista EJ, Dorsett Y, Kavathas PB, Zhou Y, Sodergren E, Weinstock GM, Snyder MP. Cell Host Microbe. 2024 Apr 10; 2024 Mar 12. PMID: 38479397.
DHX9 maintains epithelial homeostasis by restraining R-loop-mediated genomic instability in intestinal stem cells.Ren X, Liu Q, Zhou P, Zhou T, Wang D, Mei Q, Flavell RA, Liu Z, Li M, Pan W, Zhu S. Nat Commun. 2024 Apr 9; 2024 Apr 9. PMID: 38594251.
Randomized Phase II Trial of Imiquimod with or without 9-Valent HPV Vaccine versus Observation in Patients with High-grade Pre-neoplastic Cervical Lesions (NCT02864147).Sheth SS, Oh JE, Bellone S, Siegel ER, Greenman M, Mutlu L, McNamara B, Pathy S, Clark M, Azodi M, Altwerger G, Andikyan V, Huang G, Ratner E, Kim DJ, Iwasaki A, Levi AW, Buza N, Hui P, Flaherty S, Schwartz PE, Santin AD. Clin Cancer Res. 2024 Apr 9; 2024 Apr 9. PMID: 38592381.
Stem cell migration drives lung repair in living mice.Chioccioli M, Liu S, Magruder S, Tata A, Borriello L, McDonough JE, Konkimalla A, Kim SH, Nouws J, Gonzalez DG, Traub B, Ye X, Yang T, Entenberg DR, Krishnaswamy S, Hendry CE, Kaminski N, Tata PR, Sauler M. Dev Cell. 2024 Apr 8; 2024 Feb 19. PMID: 38377991.
Gene trajectory inference for single-cell data by optimal transport metrics.Qu R, Cheng X, Sefik E, Stanley Iii JS, Landa B, Strino F, Platt S, Garritano J, Odell ID, Coifman R, Flavell RA, Myung P, Kluger Y. Nat Biotechnol. 2024 Apr 5; 2024 Apr 5. PMID: 38580861.
Apoptotic cell identity induces distinct functional responses to IL-4 in efferocytic macrophages.Liebold I, Al Jawazneh A, Casar C, Lanzloth C, Leyk S, Hamley M, Wong MN, Kylies D, Gräfe SK, Edenhofer I, Aranda-Pardos I, Kriwet M, Haas H, Krause J, Hadjilaou A, Schromm AB, Richardt U, Eggert P, Tappe D, Weidemann SA, Ghosh S, Krebs CF, A-Gonzalez N, Worthmann A, Lohse AW, Huber S, Rothlin CV, Puelles VG, Jacobs T, Gagliani N, Bosurgi L. Science. 2024 Apr 5; 2024 Apr 5. PMID: 38574142.
Parasympathetic neurons derived from human pluripotent stem cells model human diseases and development.Wu HF, Saito-Diaz K, Huang CW, McAlpine JL, Seo DE, Magruder DS, Ishan M, Bergeron HC, Delaney WH, Santori FR, Krishnaswamy S, Hart GW, Chen YW, Hogan RJ, Liu HX, Ivanova NB, Zeltner N. Cell Stem Cell. 2024 Apr 4; 2024 Apr 4. PMID: 38608707.
Loss of function of metabolic traits in typhoidal Salmonella without apparent genome degradation.Machado LFM, Galán JE. mBio. 2024 Apr 4; 2024 Apr 4. PMID: 38572992.
"Rounding Third Base and Heading Home": Arthritis & Rheumatology in 2024.Solomon DH, Kaplan MJ, Nigrovic PA, Bucala R. Arthritis Rheumatol. 2024 Apr 4; 2024 Apr 4. PMID: 38572586.
Clinical Predictors of Survival in Patients With BRAFV600-Mutated Metastatic Melanoma Treated With Combined BRAF and MEK Inhibitors After Immune Checkpoint Inhibitors.Kahn AM, Perry CJ, Etts K, Kluger H, Sznol M. Oncologist. 2024 Apr 4. PMID: 37971411.
Inferring B Cell Phylogenies from Paired H and L Chain BCR Sequences with Dowser.Jensen CG, Sumner JA, Kleinstein SH, Hoehn KB. J Immunol. 2024 Apr 1; 2024 Apr 1. PMID: 38557795.
A host-microbiota interactome reveals extensive transkingdom connectivity.Sonnert ND, Rosen CE, Ghazi AR, Franzosa EA, Duncan-Lowey B, González-Hernández JA, Huck JD, Yang Y, Dai Y, Rice TA, Nguyen MT, Song D, Cao Y, Martin AL, Bielecka AA, Fischer S, Guan C, Oh J, Huttenhower C, Ring AM, Palm NW. Nature. 2024 Apr; 2024 Mar 20. PMID: 38509360.
HIF-1α Mediates Immunosuppression and Chemoresistance in Colorectal Cancer by Inhibiting CXCL9, -10 and -11.Su Y, Liu J, Tian Y, Dong H, Shi M, Zhang J, Li W, Huang Q, Xiang N, Wang C, Liu J, He L, Hu L, Haberman AM, Liu H, Yang X. Biomed Pharmacother. 2024 Apr; 2024 Mar 13. PMID: 38484558.
Compartmentalized ocular lymphatic system mediates eye-brain immunity.Yin X, Zhang S, Lee JH, Dong H, Mourgkos G, Terwilliger G, Kraus A, Geraldo LH, Poulet M, Fischer S, Zhou T, Mohammed FS, Zhou J, Wang Y, Malloy S, Rohner N, Sharma L, Salinas I, Eichmann A, Thomas JL, Saltzman WM, Huttner A, Zeiss C, Ring A, Iwasaki A, Song E. Nature. 2024 Apr; 2024 Feb 28. PMID: 38418880.
Cutting Edge: Phagosome-associated Autophagosomes Containing Antigens and Proteasomes Drive TAP-Independent Cross-Presentation.Sengupta D, Galicia-Pereyra R, Han P, Graham M, Liu X, Arshad N, Cresswell P. J Immunol. 2024 Apr 1. PMID: 38353614.
A small molecule macrophage migration inhibitory factor agonist ameliorates age-related myocardial intolerance to ischemia-reperfusion insults via metabolic regulation.Wang H, Slotabec L, Didik S, Li Z, Leng L, Zhao B, Bucala R, Li J. Metabolism. 2024 Apr; 2024 Jan 15. PMID: 38232801.
IL-10 dampens antitumor immunity and promotes liver metastasis via PD-L1 induction.Shiri AM, Zhang T, Bedke T, Zazara DE, Zhao L, Lücke J, Sabihi M, Fazio A, Zhang S, Tauriello DVF, Batlle E, Steglich B, Kempski J, Agalioti T, Nawrocki M, Xu Y, Riecken K, Liebold I, Brockmann L, Konczalla L, Bosurgi L, Mercanoglu B, Seeger P, Küsters N, Lykoudis PM, Heumann A, Arck PC, Fehse B, Busch P, Grotelüschen R, Mann O, Izbicki JR, Hackert T, Flavell RA, Gagliani N, Giannou AD, Huber S. J Hepatol. 2024 Apr; 2023 Dec 30. PMID: 38160941.
Prominent role of gut dysbiosis in the pathogenesis of cystic fibrosis-related liver disease in mice.Bertolini A, Nguyen M, Zehra SA, Taleb SA, Bauer-Pisani T, Palm N, Strazzabosco M, Fiorotto R. J Hepatol. 2024 Mar 28; 2024 Mar 28. PMID: 38554847.
Tumor Necrosis Factor Receptor-2 Signals Clear-Cell Renal Carcinoma Proliferation via Phosphorylated 4E Binding Protein-1 and Mitochondrial Gene Translation.Al-Lamki RS, Tolkovsky AM, Alawwami M, Lu W, Field SF, Wang J, Pober JS, Bradley JR. Am J Pathol. 2024 Mar 25; 2024 Mar 25. PMID: 38537932.
A multi-omics systems vaccinology resource to develop and test computational models of immunity.Shinde P, Soldevila F, Reyna J, Aoki M, Rasmussen M, Willemsen L, Kojima M, Ha B, Greenbaum JA, Overton JA, Guzman-Orozco H, Nili S, Orfield S, Gygi JP, da Silva Antunes R, Sette A, Grant B, Olsen LR, Konstorum A, Guan L, Ay F, Kleinstein SH, Peters B. Cell Rep Methods. 2024 Mar 25; 2024 Mar 14. PMID: 38490204.
Intestinal tuft cell immune privilege enables norovirus persistence.Strine MS, Fagerberg E, Darcy PW, Barrón GM, Filler RB, Alfajaro MM, D'Angelo-Gavrish N, Wang F, Graziano VR, Menasché BL, Damo M, Wang YT, Howitt MR, Lee S, Joshi NS, Mucida D, Wilen CB. Sci Immunol. 2024 Mar 22; 2024 Mar 22. PMID: 38517952.
Digital spatial proteomic profiling reveals immune checkpoints as biomarkers in lymphoid aggregates and tumor microenvironment of desmoplastic melanoma.Su DG, Schoenfeld DA, Ibrahim W, Cabrejo R, Djureinovic D, Baumann R, Rimm DL, Khan SA, Halaban R, Kluger HM, Olino K, Galan A, Clune J. J Immunother Cancer. 2024 Mar 21; 2024 Mar 21. PMID: 38519058.
Bioorthogonal click labeling of an amber-free HIV-1 provirus for in-virus single molecule imaging.Ao Y, Grover JR, Gifford L, Han Y, Zhong G, Katte R, Li W, Bhattacharjee R, Zhang B, Sauve S, Qin W, Ghimire D, Haque MA, Arthos J, Moradi M, Mothes W, Lemke EA, Kwong PD, Melikyan GB, Lu M. Cell Chem Biol. 2024 Mar 21; 2024 Jan 16. PMID: 38232732.
RORγt up-regulates RAG gene expression in DP thymocytes to expand the Tcra repertoire.Naik AK, Dauphars DJ, Corbett E, Simpson L, Schatz DG, Krangel MS. Sci Immunol. 2024 Mar 15; 2024 Mar 15. PMID: 38489350.
Mechanosensing regulates tissue repair program in macrophages.Meizlish ML, Kimura Y, Pope SD, Matta R, Kim C, Philip NH, Meyaard L, Gonzalez A, Medzhitov R. Sci Adv. 2024 Mar 15; 2024 Mar 13. PMID: 38478620.
Bioluminescence imaging reveals enhanced SARS-CoV-2 clearance in mice with combinatorial regimens.Ullah I, Escudie F, Scandale I, Gilani Z, Gendron-Lepage G, Gaudette F, Mowbray C, Fraisse L, Bazin R, Finzi A, Mothes W, Kumar P, Chatelain E, Uchil PD. iScience. 2024 Mar 15; 2024 Jan 30. PMID: 38361624.
Factors Associated With Long COVID: Insights From Two Nationwide Surveys.Wu Y, Sawano M, Wu Y, Shah RM, Bishop P, Iwasaki A, Krumholz HM. Am J Med. 2024 Mar 14; 2024 Mar 14. PMID: 38490304.
A scalable and cost-efficient rRNA depletion approach to enrich RNAs for molecular biology investigations.Singh A, Xue A, Tai J, Mbadugha F, Obi P, Mascarenhas R, Tyagi A, Siena A, Chen YG. RNA. 2024 Mar 14; 2024 Mar 14. PMID: 38485192.
Plasma Human Immunodeficiency Virus 1 Soluble Glycoprotein 120 Association With Correlates of Immune Dysfunction and Inflammation in Antiretroviral Therapy-Treated Individuals With Undetectable Viremia.Benlarbi M, Richard J, Bourassa C, Tolbert WD, Chartrand-Lefebvre C, Gendron-Lepage G, Sylla M, El-Far M, Messier-Peet M, Guertin C, Turcotte I, Fromentin R, Verly MM, Prévost J, Clark A, Mothes W, Kaufmann DE, Maldarelli F, Chomont N, Bégin P, Tremblay C, Baril JG, Trottier B, Trottier S, Duerr R, Pazgier M, Durand M, Finzi A. J Infect Dis. 2024 Mar 14. PMID: 38035854.
Emerging Cerebrospinal Fluid Biomarkers of Disease Activity and Progression in Multiple Sclerosis.Cross AH, Gelfand JM, Thebault S, Bennett JL, von Büdingen HC, Cameron B, Carruthers R, Edwards K, Fallis R, Gerstein R, Giacomini PS, Greenberg B, Hafler DA, Ionete C, Kaunzner UW, Kodama L, Lock C, Longbrake EE, Musch B, Pardo G, Piehl F, Weber MS, Yuen S, Ziemssen T, Bose G, Freedman MS, Anania VG, Ramesh A, Winger RC, Jia X, Herman A, Harp C, Bar-Or A. JAMA Neurol. 2024 Mar 11; 2024 Mar 11. PMID: 38466277.
Acute Pulmonary Injury in Hematology Patients Supported with Pathogen Reduced and Conventional Platelet Components.Wheeler AP, Snyder EL, Refaai MA, Cohn CS, Poisson J, Fontaine MJ, Sehl M, Nooka AK, Uhl L, Spinella PC, Fenelus M, Liles DK, Coyle T, Becker J, Jeng MR, Gehrie EA, Spencer BR, Young PP, Johnson AD, O'Brien J, Schiller GJ, Roback JD, Malynn E, Jackups R, Avecilla S, Liu K, Bentow S, Varrone J, Benjamin RJ, Corash L. Blood Adv. 2024 Mar 6; 2024 Mar 6. PMID: 38447116.
How Far We've Come.Sznol M, Weber JS. Cancer J. 2024 Mar-Apr 01. PMID: 38527256.
Epistatic pathways can drive HIV-1 escape from integrase strand transfer inhibitors.Hikichi Y, Grover JR, Schäfer A, Mothes W, Freed EO. Sci Adv. 2024 Mar; 2024 Mar 1. PMID: 38427738.
IL-10 constrains sphingolipid metabolism to limit inflammation.York AG, Skadow MH, Oh J, Qu R, Zhou QD, Hsieh WY, Mowel WK, Brewer JR, Kaffe E, Williams KJ, Kluger Y, Smale ST, Crawford JM, Bensinger SJ, Flavell RA. Nature. 2024 Mar; 2024 Feb 21. PMID: 38383790.
Memory B cell subsets have divergent developmental origins that are coupled to distinct imprinted epigenetic states.Callahan D, Smita S, Joachim S, Hoehn K, Kleinstein S, Weisel F, Chikina M, Shlomchik M. Nat Immunol. 2024 Mar; 2024 Jan 10. PMID: 38200277.
Immunotherapy Initiation at the End of Life in Patients With Metastatic Cancer in the US.Kerekes DM, Frey AE, Prsic EH, Tran TT, Clune JE, Sznol M, Kluger HM, Forman HP, Becher RD, Olino KL, Khan SA. JAMA Oncol. 2024 Mar 1. PMID: 38175659.
Objective Analysis and Clinical Significance of the Spatial Tumor-Infiltrating Lymphocyte Patterns in Non-Small Cell Lung Cancer.Lopez de Rodas M, Wang Y, Peng G, Gu J, Mino-Kenudson M, Riess JW, Velcheti V, Hellmann M, Gainor JF, Zhao H, Schalper KA. Clin Cancer Res. 2024 Mar 1. PMID: 38127300.
Educational Review: Clinical Application of Immune Checkpoint Blockade for the Treatment of Melanoma.Su D, Kluger H, Olino K. Ann Surg Oncol. 2024 Mar; 2023 Nov 21. PMID: 37989956.
The Emerging Spectrum of Somatic Mutation in Rheumatic Disease: Clonal Hematopoiesis Connects Aging With Giant Cell Arteritis.Bucala R, Tsao BP. Arthritis Rheumatol. 2024 Mar; 2024 Jan 3. PMID: 37961826.
Circulating Tumor Reactive KIR+CD8+ T cells Suppress Anti-Tumor Immunity in Patients with Melanoma.Hafler D, Lu B, Lucca L, Lewis W, Wang J, Nogeuira C, Heer S, Axisa PP, Buitrago-Pocasangre N, Pham G, Kojima M, Wei W, Aizenbud L, Bacchiocchi A, Zhang L, Walewski J, Chiang V, Olino K, Clune J, Halaban R, Kluger Y, Coyle A, Kisielow J, Obermair FJ, Kluger H. Res Sq. 2024 Feb 28; 2024 Feb 28. PMID: 38464315.
The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases.Sumida TS, Cheru NT, Hafler DA. Nat Rev Immunol. 2024 Feb 19; 2024 Feb 19. PMID: 38374298.
Cutaneous diatoms from diatomaceous earth mimicking myiasis infection.Roy SF, Micevic G, McNiff JM, Christensen SR, Cowper SE. Pathology. 2024 Feb 17; 2024 Feb 17. PMID: 38471986.
Decoding the autoantibody reactome.Jaycox JR, Dai Y, Ring AM. Science. 2024 Feb 16; 2024 Feb 15. PMID: 38359108.
Cell surface RNAs control neutrophil recruitment.Zhang N, Tang W, Torres L, Wang X, Ajaj Y, Zhu L, Luan Y, Zhou H, Wang Y, Zhang D, Kurbatov V, Khan SA, Kumar P, Hidalgo A, Wu D, Lu J. Cell. 2024 Feb 15; 2024 Jan 22. PMID: 38262409.
Host-Microbe Multiomic Profiling Reveals Age-Dependent COVID-19 Immunopathology.Van Phan H, Tsitsiklis A, Maguire CP, Haddad EK, Becker PM, Kim-Schulze S, Lee B, Chen J, Hoch A, Pickering H, Van Zalm P, Altman MC, Augustine AD, Calfee CS, Bosinger S, Cairns C, Eckalbar W, Guan L, Jayavelu ND, Kleinstein SH, Krammer F, Maecker HT, Ozonoff A, Peters B, Rouphael N, Montgomery RR, Reed E, Schaenman J, Steen H, Levy O, Diray-Arce J, Langelier CR. medRxiv. 2024 Feb 13; 2024 Feb 13. PMID: 38405760.
Interferon-stimulated neutrophils as a predictor of immunotherapy response.Benguigui M, Cooper TJ, Kalkar P, Schif-Zuck S, Halaban R, Bacchiocchi A, Kamer I, Deo A, Manobla B, Menachem R, Haj-Shomaly J, Vorontsova A, Raviv Z, Buxbaum C, Christopoulos P, Bar J, Lotem M, Sznol M, Ariel A, Shen-Orr SS, Shaked Y. Cancer Cell. 2024 Feb 12; 2024 Jan 4. PMID: 38181798.
CD23(+)IgG1(+) memory B cells are poised to switch to pathogenic IgE production in food allergy.Ota M, Hoehn KB, Fernandes-Braga W, Ota T, Aranda CJ, Friedman S, Miranda-Waldetario MGC, Redes J, Suprun M, Grishina G, Sampson HA, Malbari A, Kleinstein SH, Sicherer SH, Curotto de Lafaille MA. Sci Transl Med. 2024 Feb 7; 2024 Feb 7. PMID: 38324641.
Immunotherapy utilization in stage IIIA melanoma: less may be more.Frey AE, Kerekes DM, Khan SA, Tran TT, Kluger HM, Clune JE, Ariyan S, Sznol M, Ishizuka JJ, Olino KL. Front Oncol. 2024; 2024 Feb 6. PMID: 38380358.
Prior Influenza Infection Mitigates SARS-CoV-2 Disease in Syrian Hamsters.Di Pietro C, Haberman AM, Lindenbach BD, Smith PC, Bruscia EM, Allore HG, Vander Wyk B, Tyagi A, Zeiss CJ. Viruses. 2024 Feb 3; 2024 Feb 3. PMID: 38400021.
Human genetic errors of immunity illuminate an adaptive arsenal model of rapid defenses.Lucas CL. Trends Immunol. 2024 Feb; 2024 Jan 31. PMID: 38302340.
Granulomatous secondary syphilis with pulmonary involvement.Johnston AD, Roy SF, McNiff J, Petrazzuoli M. JAAD Case Rep. 2024 Feb; 2023 Dec 2. PMID: 38292581.
PD-1H/VISTA mediates immune evasion in acute myeloid leukemia.Kim TK, Han X, Hu Q, Vandsemb EN, Fielder CM, Hong J, Kim KW, Mason EF, Plowman RS, Wang J, Wang Q, Zhang JP, Badri T, Sanmamed MF, Zheng L, Zhang T, Alawa J, Lee SW, Zeidan AM, Halene S, Pillai MM, Chandhok NS, Lu J, Xu ML, Gore SD, Chen L. J Clin Invest. 2024 Feb 1; 2024 Feb 1. PMID: 38060328.
Core Needle Biopsies as an Alternative Source for Ex Vivo Expanded TIL for Adoptive Cell Therapy in Triple-Negative Breast Cancer.Coman MM, Pusztai L, Hooley R, Andreveja L, Kim L, Joshi N, Bersenev A, Krause D, Park TS. J Immunother. 2024 Feb-Mar 01; 2023 Nov 22. PMID: 37991241.
Nmes1 is a novel regulator of mucosal response influencing intestinal healing potential.Hamley M, Leyk S, Casar C, Liebold I, Jawazneh AA, Lanzloth C, Böttcher M, Haas H, Richardt U, Rothlin CV, Jacobs T, Huber S, Adlung L, Pelczar P, Henao-Mejia J, Bosurgi L. Eur J Immunol. 2024 Feb; 2023 Nov 28. PMID: 37971166.
Biallelic CRELD1 variants cause a multisystem syndrome, including neurodevelopmental phenotypes, cardiac dysrhythmias, and frequent infections.Jeffries L, Mis EK, McWalter K, Donkervoort S, Brodsky NN, Carpier JM, Ji W, Ionita C, Roy B, Morrow JS, Darbinyan A, Iyer K, Aul RB, Banka S, Chao KR, Cobbold L, Cohen S, Custodio HM, Drummond-Borg M, Elmslie F, Finanger E, Hainline BE, Helbig I, Hewson S, Hu Y, Jackson A, Josifova D, Konstantino M, Leach ME, Mak B, McCormick D, McGee E, Nelson S, Nguyen J, Nugent K, Ortega L, Goodkin HP, Roeder E, Roy S, Sapp K, Saade D, Sisodiya SM, Stals K, Towner S, Wilson W, Khokha MK, Bönnemann CG, Lucas CL, Lakhani SA. Genet Med. 2024 Feb; 2023 Nov 7. PMID: 37947183.
TREM2 function in glioblastoma immune microenvironment: can we distinguish reality from illusion?Ghosh S, Rothlin CV. Neuro Oncol. 2024 Jan 30; 2024 Jan 30. PMID: 38290471.
Nutrient-derived signals regulate eosinophil adaptation to the small intestine.I Kutyavin V, Korn LL, Medzhitov R. Proc Natl Acad Sci U S A. 2024 Jan 30; 2024 Jan 25. PMID: 38271336.
A compact regulatory RNA element in mouse Hsp70 mRNA.Wang W, Liu F, Ugalde MV, Pyle AM. NAR Mol Med. 2024 Jan; 2024 Jan 29. PMID: 38318492.
Language model-based B cell receptor sequence embeddings can effectively encode receptor specificity.Wang M, Patsenker J, Li H, Kluger Y, Kleinstein SH. Nucleic Acids Res. 2024 Jan 25. PMID: 38109302.
Potential role of RhoA GTPase regulation in type interferon signaling in systemic lupus erythematosus.Fan W, Wei B, Chen X, Zhang Y, Xiao P, Li K, Zhang YQ, Huang J, Leng L, Bucala R. Arthritis Res Ther. 2024 Jan 20; 2024 Jan 20. PMID: 38243295.
Platelet Mitochondrial Fusion and Function in Vascular Integrity.Tyagi T, Yarovinsky TO, Faustino EVS, Hwa J. Circ Res. 2024 Jan 19; 2024 Jan 18. PMID: 38236952.
"Deficiency in ELF4, X-Linked": a Monogenic Disease Entity Resembling Behçet's Syndrome and Inflammatory Bowel Disease.Olyha SJ, O'Connor SK, Kribis M, Bucklin ML, Uthaya Kumar DB, Tyler PM, Alam F, Jones KM, Sheikha H, Konnikova L, Lakhani SA, Montgomery RR, Catanzaro J, Du H, DiGiacomo DV, Rothermel H, Moran CJ, Fiedler K, Warner N, Hoppenreijs EPAH, van der Made CI, Hoischen A, Olbrich P, Neth O, Rodríguez-Martínez A, Lucena Soto JM, van Rossum AMC, Dalm VASH, Muise AM, Lucas CL. J Clin Immunol. 2024 Jan 17; 2024 Jan 17. PMID: 38231408.
Generation and optimization of off-the-shelf immunotherapeutics targeting TCR-Vβ2+ T cell malignancy.Ren J, Liao X, Lewis JM, Chang J, Qu R, Carlson KR, Foss F, Girardi M. Nat Commun. 2024 Jan 15; 2024 Jan 15. PMID: 38225288.
Impact of COVID-19 vaccination on symptoms and immune phenotypes in vaccine-naïve individuals with Long COVID.Grady CB, Bhattacharjee B, Silva J, Jaycox J, Lee LW, Monteiro VS, Sawano M, Massey D, Caraballo C, Gehlhausen JR, Tabachnikova A, Mao T, Lucas C, Peña-Hernandez MA, Xu L, Tzeng TJ, Takahashi T, Herrin J, Güthe DB, Akrami A, Assaf G, Davis H, Harris K, McCorkell L, Schulz WL, Grffin D, Wei H, Ring AM, Guan L, Cruz CD, Iwasaki A, Krumholz HM. medRxiv. 2024 Jan 12; 2024 Jan 12. PMID: 38260484.
Intracellular calcium links milk stasis to lysosome-dependent cell death during early mammary gland involution.Jeong J, Lee J, Talaia G, Kim W, Song J, Hong J, Yoo K, Gonzalez DG, Athonvarangkul D, Shin J, Dann P, Haberman AM, Kim LK, Ferguson SM, Choi J, Wysolmerski J. Cell Mol Life Sci. 2024 Jan 12; 2024 Jan 12. PMID: 38212474.
mosGILT controls innate immunity and germ cell development in Anopheles gambiae.Arora G, Tang X, Cui Y, Yang J, Chuang YM, Joshi J, Sajid A, Dong Y, Cresswell P, Dimopoulos G, Fikrig E. BMC Genomics. 2024 Jan 9; 2024 Jan 9. PMID: 38191283.
Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection.Torcellan T, Friedrich C, Doucet-Ladevèze R, Ossner T, Solé VV, Riedmann S, Ugur M, Imdahl F, Rosshart SP, Arnold SJ, Gomez de Agüero M, Gagliani N, Flavell RA, Backes S, Kastenmüller W, Gasteiger G. Immunity. 2024 Jan 9; 2023 Dec 28. PMID: 38157853.
A Phase II Trial of the CD40 Agonistic Antibody Sotigalimab (APX005M) in Combination with Nivolumab in Subjects with Metastatic Melanoma with Confirmed Disease Progression on Anti-PD-1 Therapy.Weiss SA, Sznol M, Shaheen M, Berciano-Guerrero MÁ, Couselo EM, Rodríguez-Abreu D, Boni V, Schuchter LM, Gonzalez-Cao M, Arance A, Wei W, Ganti AK, Hauke RJ, Berrocal A, Iannotti NO, Hsu FJ, Kluger HM. Clin Cancer Res. 2024 Jan 5. PMID: 37535056.
MIF contribution to progressive brain diseases.Matejuk A, Benedek G, Bucala R, Matejuk S, Offner H, Vandenbark AA. J Neuroinflammation. 2024 Jan 4; 2024 Jan 4. PMID: 38178143.
Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study.Ozonoff A, Jayavelu ND, Liu S, Melamed E, Milliren CE, Qi J, Geng LN, McComsey GA, Cairns CB, Baden LR, Schaenman J, Shaw AC, Samaha H, Seyfert-Margolis V, Krammer F, Rosen LB, Steen H, Syphurs C, Dandekar R, Shannon CP, Sekaly RP, Ehrlich LIR, Corry DB, Kheradmand F, Atkinson MA, Brakenridge SC, Higuita NIA, Metcalf JP, Hough CL, Messer WB, Pulendran B, Nadeau KC, Davis MM, Sesma AF, Simon V, van Bakel H, Kim-Schulze S, Hafler DA, Levy O, Kraft M, Bime C, Haddad EK, Calfee CS, Erle DJ, Langelier CR, Eckalbar W, Bosinger SE, Peters B, Kleinstein SH, Reed EF, Augustine AD, Diray-Arce J, Maecker HT, Altman MC, Montgomery RR, Becker PM, Rouphael N. Nat Commun. 2024 Jan 3; 2024 Jan 3. PMID: 38172101.
Knocking out Fkbp51 decreases CCl(4)-induced liver injury through enhancement of mitochondrial function and Parkin activity.Qiu B, Zhong Z, Dou L, Xu Y, Zou Y, Weldon K, Wang J, Zhang L, Liu M, Williams KE, Spence JP, Bell RL, Lai Z, Yong W, Liang T. Cell Biosci. 2024 Jan 2; 2024 Jan 2. PMID: 38167156.
NCCN Guidelines® Insights: Merkel Cell Carcinoma, Version 1.2024.Schmults CD, Blitzblau R, Aasi SZ, Alam M, Amini A, Bibee K, Bolotin D, Bordeaux J, Chen PL, Contreras CM, DiMaio D, Donigan JM, Farma JM, Ghosh K, Harms K, Ho AL, Lukens JN, Manber S, Mark L, Medina T, Nehal KS, Nghiem P, Olino K, Park S, Patel T, Puzanov I, Rich J, Sekulic A, Shaha AR, Srivastava D, Thomas V, Tomblinson C, Venkat P, Xu YG, Yu S, Yusuf M, McCullough B, Espinosa S. J Natl Compr Canc Netw. 2024 Jan. PMID: 38244274.
Allogeneic transplantation and cellular therapies in cutaneous T-cell lymphoma.Goyal A, Foss F. Expert Rev Anticancer Ther. 2024 Jan-Feb; 2024 Feb 12. PMID: 38224371.
B cell phylogenetics in the single cell era.Hoehn KB, Kleinstein SH. Trends Immunol. 2024 Jan; 2023 Dec 27. PMID: 38151443.
A multicenter phase Ib trial of the histone deacetylase inhibitor entinostat in combination with pembrolizumab in patients with myelodysplastic syndromes/neoplasms or acute myeloid leukemia refractory to hypomethylating agents.Bewersdorf JP, Shallis RM, Sharon E, Park S, Ramaswamy R, Roe CE, Irish JM, Caldwell A, Wei W, Yacoub A, Madanat YF, Zeidner JF, Altman JK, Odenike O, Yerrabothala S, Kovacsovics T, Podoltsev NA, Halene S, Little RF, Piekarz R, Gore SD, Kim TK, Zeidan AM. Ann Hematol. 2024 Jan; 2023 Dec 1. PMID: 38036712.
Guidelines on the use of sex and gender in cardiovascular research.Usselman CW, Lindsey ML, Robinson AT, Habecker BA, Taylor CE, Merryman WD, Kimmerly D, Bender JR, Regensteiner JG, Moreau KL, Pilote L, Wenner MM, O'Brien M, Yarovinsky TO, Stachenfeld NS, Charkoudian N, Denfeld QE, Moreira-Bouchard JD, Pyle WG, DeLeon-Pennell KY. Am J Physiol Heart Circ Physiol. 2024 Jan 1; 2023 Nov 24. PMID: 37999647.
Pitfalls of PRAME Immunohistochemistry in a Large Series of Melanocytic and Nonmelanocytic Lesions With Literature Review.Turner N, Ko CJ, McNiff JM, Galan A. Am J Dermatopathol. 2024 Jan 1. PMID: 37982498.
Extracellular macrophage migration inhibitory factor (MIF) downregulates adipose hormone-sensitive lipase (HSL) and contributes to obesity.Chen L, Li L, Cui D, Huang Y, Tong H, Zabihi H, Wang S, Qi Y, Lakowski T, Leng L, Liu S, Wu H, Young LH, Bucala R, Qi D. Mol Metab. 2024 Jan; 2023 Nov 5. PMID: 37935315.
Increased Lymphocyte Infiltration in NSCLC Neoadjuvant Chemo-Immunotherapy Non-responders: A Biomarker of T-Cell Dysfunction and Prognosis?Woodard GA, Cho C, Chen L. Ann Surg Oncol. 2024 Jan; 2023 Oct 29. PMID: 37899411.
Normal B cells express ZAP70 in chronic lymphocytic leukemia: A link between autoimmunity and lymphoproliferation?Ghergus D, Martin M, Knapp AM, Delmotte F, Joublin-Delavat A, Jung S, Schickel JN, Mendel I, Dupuis A, Drénou B, Ghesquières H, Salles G, Baseggio L, Herbrecht R, Korganow AS, Vallat L, Soulas-Sprauel P, Meffre E, Martin T. Am J Hematol. 2024 Jan; 2023 Oct 19. PMID: 37853951.
Allogeneic stem cell transplant for treatment of mycosis fungoides and Sezary syndrome: a systematic review and meta-analysis.Goyal A, O'Leary D, Foss F. Bone Marrow Transplant. 2024 Jan; 2023 Oct 18. PMID: 37853164.
PI3Kδ Pathway Dysregulation and Unique Features of Its Inhibition by Leniolisib in Activated PI3Kδ Syndrome and Beyond.Cant AJ, Chandra A, Munro E, Rao VK, Lucas CL. J Allergy Clin Immunol Pract. 2024 Jan; 2023 Sep 28. PMID: 37777067.
Bioactive signalling lipids as drivers of chronic liver diseases.Kaffe E, Tisi A, Magkrioti C, Aidinis V, Mehal WZ, Flavell RA, Maccarrone M. J Hepatol. 2024 Jan; 2023 Sep 21. PMID: 37741346.
Immunology for the Rheumatologist: Arthritis & Rheumatology Introduces a New Problem-Based Immunology Review Series With Great Educational Potential.Bucala R, Solomon DH. Arthritis Rheumatol. 2024 Jan; 2023 Oct 23. PMID: 37655656.
Immune Inhibitory Molecule PD-1 Homolog (VISTA) Colocalizes with CD11b Myeloid Cells in Melanoma and Is Associated with Poor Outcomes.Vesely MD, Kidacki M, Gaule P, Gupta S, Chan NNN, Han X, Yeung JT, Chen L. J Invest Dermatol. 2024 Jan; 2023 Aug 8. PMID: 37562584.

2023

Metabolic fitness of IgA(+) plasma cells in the gut requires DOCK8.Zhang B, Chen S, Yin X, McBride CD, Gertie JA, Yurieva M, Bielecka AA, Hoffmann B, Travis Hinson J, Grassmann J, Xu L, Siniscalco ER, Soldatenko A, Hoyt L, Joseph J, Norton EB, Uthaman G, Palm NW, Liu E, Eisenbarth SC, Williams A. Mucosal Immunol. 2023 Dec 28; 2023 Dec 28. PMID: 38159726.
Host-Microbe Multi-omic Profiling Identifies a Unique Program of COVID-19 Inflammatory Dysregulation in Solid Organ Transplant Recipients.Langelier C, Pickering H, Schaenman J, Phan H, Maguire C, Tsitsiklis A, Rouphael N, Higuita N, Atkinson M, Breckenridge S, Fung M, Messer W, Salehi-Rad R, Altman M, Becker P, Bosinger S, Eckalbar W, Hoch A, Jayavelu N, Kim-Schulze S, Jenkins M, Kleinstein S, Krammer F, Maecker H, Ozonoff A, Diray-Arce J, Shaw A, Baden L, Levy O, Reed E. Res Sq. 2023 Dec 20; 2023 Dec 20. PMID: 38196658.
Targeting interleukin (IL)-4/IL-13 in immune checkpoint inhibitor-induced bullous pemphigoid: a cautionary note on the beneficial effect of T helper 2 immunity in melanoma and immunotherapy: reply from the authors.Shipman WD, Singh K, Cohen JM, Leventhal J, Damsky W, Tomayko MM. Br J Dermatol. 2023 Dec 20. PMID: 37947404.
scNAT: a deep learning method for integrating paired single-cell RNA and T cell receptor sequencing profiles.Zhu B, Wang Y, Ku LT, van Dijk D, Zhang L, Hafler DA, Zhao H. Genome Biol. 2023 Dec 18; 2023 Dec 18. PMID: 38111007.
Author Correction: A ZFYVE21-Rubicon-RNF34 signaling complex promotes endosome-associated inflammasome activity in endothelial cells.Li X, Jiang Q, Song G, Barkestani MN, Wang Q, Wang S, Fan M, Fang C, Jiang B, Johnson J, Geirsson A, Tellides G, Pober JS, Jane-Wit D. Nat Commun. 2023 Dec 18; 2023 Dec 18. PMID: 38110370.
Macrophages control pathological interferon responses during viral respiratory infection.Hoagland DA, Rodríguez-Morales P, Mann AO, Yu S, Lai A, Vazquez AB, Pope SD, Lim J, Li S, Zhang X, Li MO, Medzhitov R, Franklin RA. bioRxiv. 2023 Dec 17; 2023 Dec 17. PMID: 38168230.
Distinct hypoxia-induced translational profiles of embryonic and adult-derived macrophages.Wilcox NS, Yarovinsky TO, Pandya P, Ramgolam VS, Moro A, Wu Y, Nicoli S, Hirschi KK, Bender JR. iScience. 2023 Dec 15; 2023 Sep 21. PMID: 38047075.
Early cellular and molecular signatures correlate with severity of West Nile virus infection.Lee HJ, Zhao Y, Fleming I, Mehta S, Wang X, Wyk BV, Ronca SE, Kang H, Chou CH, Fatou B, Smolen KK, Levy O, Clish CB, Xavier RJ, Steen H, Hafler DA, Love JC, Shalek AK, Guan L, Murray KO, Kleinstein SH, Montgomery RR. iScience. 2023 Dec 15; 2023 Nov 2. PMID: 38047068.