Vincent James Quagliarello MD

Professor of Medicine (Infectious Diseases); Clinical Chief, Infectious Diseases

Research Interests

Observational research methods for understanding infectious disease

Research Summary

Dr. Quagliarello's current research interest is utilizing observational research methods (both retrospective and prospective cohort designs) to understand infectious disease. Recent research projects have focused on community acquired bacterial meningitis (including studies on prognostic staging, utility of head CT before LP in suspected meningitis, identification of the causes and timing of death, and the diagnostic accuracy of bedside meningeal signs), native valve endocarditis (a study using prognostic stratification to evaluate the impact of valve surgery on mortality), and risk factors for nursing home acquired pneumonia in conjunction with the Yale Program on Aging. In addition, Dr. Quagliarello's is currently conducting a large prospective cohort study examining modifiable risk factors on nursing home acquired pneumonia.

Selected Publications

  • Quagliarello V. Dissemination of Neisseria meningitis. N Engl J Med 2011;364:1573-5.
  • Quagliarello VJ, Scheld WM. Do steroids benefit patients with bacterial meningitis? Nature Rev Neuro 2010; 6:529-30.
  • Juthani-Mehta M, Quagliarello V. Infectious diseases in the nursing home setting: Challenges and opportunities for clinical investigation. Clin Infect Dis 2010: 51:931-6.
  • Quagliarello VJ, Juthani-Mehta M, Ginter S, Towle V, Allore H, Tinetti M. Pilot testing of intervention protocols to prevent pneumonia among nursing home residents. J Amer Geriatr Soc 2009; 57:1226-31.
  • Juthani-Mehta M, Tinetti M, Perrelli E, Towle V, Van Ness P, Quagliarello V. Interobserver variability in the assessment of clinical criteria for suspected urinary tract infection in nursing home residents. Infect Cont Hosp Epid 2008; 29:446-9.

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