Director, Yale Program on Aging Biostatistics Core
Director, Data Management and Statistics Core, Yale Alzheimer's Disease Research Center
Co-director of the Biostatistics and Bioinformatics Core of the Yale Transdisciplinary Collaborative Center for Precision Medicine focused on Health Disparities
Adjunct Professor, Harldsplass Deaconess Hospital, University of Bergen, Norway
Aging; Biostatistics; Frail Elderly; Geriatrics; Mathematical Concepts; Statistics as Topic
The objective of the Yale Institutional Training Grant for Infectious Disease provide greater research opportunities for Yale postdoctoral trainees to be equipped to address the myriad of unanswered questions concerning the diagnosis, etiology, treatment, prevention, and prognosis of the health problems experienced by the ever increasing number of persons. My mentorship skills will allow trainees to rigorously address the myriad of unanswered scientific questions related to infections...
Professor of Medicine (Infectious Diseases) and of Epidemiology (Microbial Diseases)
Director, Clinical and Community Research
Director, HIV in Prisons Program
Director, Community Health Care Van
Academic Icon Professor of Medicine, University of Malaya-Centre of Excellence for Research in AIDS (CERiA)
Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Behavioral Medicine; Chemicals and Drugs; Cognitive Therapy; Community Medicine; Community-Based Participatory Research; Epidemiology; Global Health; Health Care; Health Status Disparities; Healthcare Disparities; Hepatitis, Viral, Human; HIV Infections; Infectious Disease Medicine; Social Medicine
I am interested in a broad range of clinical and community research activities at the interface of infectious diseases and addiction. I have conducted innovative research in community, clinic-based and criminal justice settings, both domestically and internationally for over 25 years. I am board-certified in both Infectious Diseases and Addiction Medicine and have developed and tested numerous evidence-based interventions that are associated with improved clinical treatment outcomes for...
Associate Professor of Medicine (Infectious Diseases) and of Microbial Pathogenesis
Babesia microti; Infectious Disease Medicine; Malaria; Plasmodium falciparum
Dr. Ben Mamoun’s laboratory studies the pathogenesis of human malaria and babesiosis. The primary objectives of his research program are to identify new targets for development of potent and selective new therapies to treat these diseases and to develop a new diagnostic test for early detection of Babesia infection to prevent transfusion transmitted babesiosis. His laboratory has discovered several genes that play a critical function in Plasmodium falciparum and Babesia microti development and...
Harold W. Jockers Professor of Medicine (Rheumatology)
Deputy Dean for Faculty Affairs
Faculty; Immunity, Innate; Lyme Disease; Lyme Neuroborreliosis; Rheumatology; Tick-Borne Diseases
I am a physician-scientist with scientific expertise in the pathogenesis of tick- borne Lyme borreliosis in animal models and in humans. This infection can cause a form of chronic inflammatory pauciarticular arthritis that resembles autoimmune forms of arthritis. My research laboratory has contributed to the understanding of the roles of T cells, B cells, and innate immunity in Lyme disease pathogenesis and in prevention of infection. Recent efforts include the application of 2-photon...
Professor of Medicine (Rheumatology), of Epidemiology (Microbial Diseases) and of Pathology
Deputy Chief, Section of Rheumatology
Africa; Communicable Diseases, Emerging; Epidemiology; Global Health; Infectious Disease Medicine; Macrophage Migration-Inhibitory Factors; Malaria; Pathology; Public Health; Rheumatology; Stem Cells
My career as a physician-scientist has provided me with both the scientific and medical expertise and the mentoring skills necessary to contribute meaningfully to this training program. Since my first faculty appointment in 1991, I have trained nearly 50 scientists in my laboratory. Several of these individuals have advanced to prominent positions of medical and scientific leadership, and they include two chairs of medicine, two division chiefs in departments of medicine, a department chair in...
Professor of Pediatrics (Infectious Disease), of Epidemiology (Microbial Diseases) and of Microbial Pathogenesis
Chair, Council on African Studies, Whitney and Betty MacMillan Center for International and Area Studies
co-Director, Yale Africa Initiative
Africa, Western; Developing Countries; Ghana; Global Health; Hookworm Infections; Infectious Disease Medicine; Malaria; Microbiology; Pediatrics; Public Health; Tropical Medicine
Our research program is focused on the pathogenesis and epidemiology of globally important infectious diseases, with the ultimate goal of developing novel methods of treatment and prevention. We conduct laboratory, field and community based studies of parasitic diseases, including hookworm and malaria, which are major causes of anemia and malnutrition in resource limited countries. Laboratory research centers on identifying major parasite virulence factors, which has allowed for the development...
Associate Professor of Epidemiology (Microbial Diseases) and Associate Professor in the Institution for Social and Policy Studies
Africa South of the Sahara; Drug Resistance, Microbial; Epidemiology; Europe, Eastern; HIV Infections; Models, Biological; Molecular Epidemiology; Public Health; South America; Tuberculosis
I am an infectious disease epidemiologist with training and experience in clinical medicine, field epidemiology, and transmission dynamic modeling. My research group’s main area of focus is the emergence, spread, and control of drug resistant tuberculosis, now recognized as a major hurdle to global tuberculosis control.
My research group includes postdoctoral fellows from a diverse set of fields ranging from clinical medicine, applied mathematics, biostatistics, operations research, evolutionary...
Paul B. Beeson Professor of Medicine (Rheumatology) and Professor of Immunobiology
Section Chief, Rheumatology
Program Director, Investigative Medicine
Paul B. Beeson Professor of Medicine
Antigens, Differentiation, T-Lymphocyte; Autoimmune Diseases; Biology; Cytokines; Immunity; Investigative Techniques; Lupus Erythematosus, Systemic; Rheumatology
Dr. Craft investigates CD4 T helper cells in conventional and autoimmune responses in mice and in humans, with a primary focus upon the differentiation and function of follicular helper (Tfh) cells that promote B cell maturation in germinal centers (GC). Tfh cell dependent GC responses are critical for development of humoral immunity and B cell memory upon vaccine administration and following infection, and for driving pathogenic autoreactive B cell responses in autoimmune diseases. Dr. Craft’s...
Eugene Higgins Professor of Immunobiology and Professor of Cell Biology
Biology; Cell Biology; Endoplasmic Reticulum; Immunity; Major Histocompatibility Complex
I have been involved in the study of MHC and CD1 molecules, their assembly, peptide and lipid association, and subsequent T cell stimulation for many years, and we continue work in this field. We have identified many genes that regulate both HLA class I and class II functions. T cell recognition of MHC complexes with self- peptides underlies many T-cell mediated autoimmune diseases, and the relevance of this process to tumor and pathogen recognition is clear. We also study the action of...
Associate Professor of Epidemiology (Microbial Diseases)
Associate Professor of Medicine (Pulmonary, Critical Care, and Sleep Medicine)
Critical Care; Global Health; Mobile Applications; Tuberculosis
My current research program comprises clinical, translational, and implementation research on diagnostic evaluation and case finding of tuberculosis (TB) in resource-constrained settings. I am interested in translating how novel insights from the basic biological and behavioral sciences, and from information technology to provide useful, real-time information to clinicians and public health practitioners at the point of care. The long-term goal is to provide patient-centered diagnostic and...