The Yale Liver Center

The Yale Liver Center is one of 18 Digestive Diseases Research Core Centers (DDRCCs) supported by NIH/NIDDK. The Yale Liver Center has been funded continuously since 1984 and is one of only four that focus on the liver. The Yale Liver Center supports investigation of liver structure, function and disease. Research support is provided through the Center’s Four Core Facilities, as well as through Pilot Feasibility Projects that are offered annually.

The research base focuses on six major areas:

  • Cellular and Molecular Biology of the Liver 
  • Hepatic Transport Mechanisms
  • Basic Biology of Disease Processes
  • Studies of the Splanchnic Circulation
  • Liver Immunology
  • Liver Cancer
  • Clinical Hepatology

More than seventy-five independent principal investigators are members of the Center which involves over 20 departments at Yale including, but not limited to: Biomedical and Chemical Engineering; Cell Biology; Cellular and Molecular Physiology; Comparative Medicine; School of Public Health; Human Genetics; Immunobiology; Laboratory Medicine; Internal Medicine; Microbial Pathogenesis; Molecular, Cellular and Developmental Biology; Pathology; Pediatrics; Pharmacology; Radiology; Transplant and Surgery.

The Liver Center also supports weekly research seminars (on Tuesday afternoons) and clinical lectures (on Friday afternoons), in conjunction with the Section of Digestive Diseases, Department of Internal Medicine.


Michael H. Nathanson, M.D., Ph.D.
Michael H. Nathanson, M.D., Ph.D.
Director, Liver Center more...

Liver Center Upcoming Events


Date: September 13th, 2016
Location: TAC S247
Time: 5:00PM

Huma Cheema, MBBS, MRCP

Director, Pediatric Gastroenterology & Hepatology Division

Children’s Hospital Lahore

“Rare Pediatric Liver Diseases in Pakistan – Challenges and Opportunities”

(Host: Dr. Pramod Mistry)

Liver Center Retreat

Date: November 19th, 2016

Location: New Haven Country Club