Lawrence Howard Young MD

Professor of Medicine (Cardiology) and of Cellular and Molecular Physiology; Vice-Chairman, Department of Medicine

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Medicine, Pharmacology, and Physiology

Yale Medical Group

Office of Student ResearchCellular & Molecular Physiology: Graduate Program in Cellular and Molecular PhysiologyInternal Medicine: Cardiovascular Medicine: Yale Cardiovascular Research Center; Fellowship Training; Diabetes Research Center

Research Interests

Myocardial ischemia; Metabolic adaptation to hypoxic stress; Cardio-protection; Cardiomyopathy; LKB1-AMPK pathway; Diabetes more...


  • AB, Brown University, 1976
  • M.D., Yale University, 1980

Selected Publications

  • Qi D, Atsina K, Hu X, Wu X, Xu B, Piecychna M, Leng L, Fingerle-Rowson G, Zhang J, Bucala R, Young LH. The vestigial enzyme D-dopachrome tautomerase protects the heart against ischemic injury. J Clin Invest 2014; 124;3540-50.
  • Li J, Qi D, Cheng H, Miller EJ, Wu X, Russell, KS, Mikush N, Zhang J, Xiao L, Sherwin RS, Young LH. Urocortin 2 autocrine/paracrine and pharmacologic effects to activate AMP-activated protein kinase in the heart. PNAS 2013; 110:16133-8.
  • Zaha VG, Young LH. AMP-activated protein kinase regulation and biological actions in the heart. Circ Res. 2012; 111:800-814.



Latest News


Edit Profile