Carlo Spirli PhD

Assistant Professor of Medicine (Digestive Diseases)

Departments & Organizations

Internal Medicine: Digestive Diseases


  • BS, University of Padova, 1995
  • Ph.D., University School of Medicine, Parma, 2000

Selected Publications

  • Spirli C, Morell CM, Locatelli L, Okolicsanyi S, Ferrero C, Kim AK, Fabris L, Fiorotto R, Strazzabosco M. Cyclic AMP/PKA-dependent paradoxical activation of Raf/MEK/ERK signaling in polycystin-2 defective mice treated with Sorafenib. Hepatology. In Press
  • Spirli C, Locatelli L, Fiorotto R, Morell CM, Fabris L, Pozzan T, Strazzabosco M.Altered store operated calcium entry increases cyclic 3',5'-adenosine monophosphate production and extracellular signal-regulated kinases 1 and 2 phosphorylation in polycystin-2-defective cholangiocytes. Hepatology. 2012 55:856-68.
  • Spirli C, Okolicsanyi S, Fiorotto R, Fabris L, Cadamuro M, Lecchi S, Tian X, Somlo S, Strazzabosco M. 2010. Mammalian Target of Rapamycin Regulates Vascular Endothelial Growth Factor-Dependent Liver Cyst Growth in Polycystin-2 defective mice. Hepatology 51:1778-88



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