Peter John Tattersall, PhD

Professor of Laboratory Medicine and of Genetics

Departments & Organizations

Laboratory Medicine


Cancer Center: Virus and Other Infection-associated Cancers

Faculty Research

Molecular Virology: Virology laboratories

Office of Student Research

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Microbiology: Viruses | Molecular Cell Biology, Genetics and Development: Cell Biology; Human Disease; Molecular Mechanisms; Nuclear Dynamics; Quantitative/Systems Biology; Signal Transduction

Office of Cooperative Research


Dr. Tattersall received his B.Sc. in Molecular Biology from

the University of Glasgow, Scotland in 1968, and his doctorate from University

College, London, England, in 1971, for studies on parvoviral DNA structure,

replication and S-phase dependence, carried out at the Imperial Cancer Research

Fund (ICRF). Then followed two years of

postdoctoral fellowship at the Roche Institute of Molecular Biology, in Nutley,

New Jersey, where he worked out the structural protein strategy of these

viruses, and then two further years in Yale University’s Molecular Biophysics

and Biochemistry Department, where he formulated the rolling hairpin model for

parvoviral DNA replication.

In 1975, he returned to the UK, working at the ICRF’s Mill Hill Laboratories on

parvoviral interactions with differentiating cells. He moved back to Yale University in 1979, initially on the

faculty of the Department of Genetics and then in Laboratory Medicine, where he

was appointed professor in 1993.

His laboratory continues to focus its efforts on understanding the

molecular mechanisms by which mammalian parvoviruses target and enter

particular cell types, express their genes, take over their host cells and

replicate their own DNA.

Education & Training

PhD University of London (1971)
Postdoc Yale University
Postdoc Roche Institute of Molecular Biology

Honors & Recognition

  • Elected Fellow of the American Academy of Microbiology (2007)

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Contact Info

Peter John Tattersall, PhD
Mailing Address
Laboratory MedicinePO Box 208035
333 Cedar Street

New Haven, CT 06520-8035
Research Image 1

Left - depth-cued, space filling model of MVM, looking down the cylinder at a 5-fold symmetry axis. Upper right - cross-section of the channel down the center of the cylinder, showing two of the five β-ribbons that comprise the cylinder, with the G-rich residues, from 28 to 37 of VP2, in gray. Lower right - view down the 5-fold cylinder, with the five β-ribbons differentially shaded.