Fertilization

fertilization figure

Figure: Various phosphorylation patterns in the different regions of human spermatozoa. Phosphorylation in the principal and neck piece is a prerequisite for the sperm to fertilize.

The role of glucose during gamete fusion. In particular how glucose metabolism in sperm prior to fertilization prepares sperm for entering into the oocyte. This research involves both human and animal models.

Particular focus is now being made on investigating protein phosphorylation patterns in sperm that equip them for the fertilization process and how the spermatozoa is able to control phosphorylation in the different compartments that make it up.