Raphael Sherak, MD, MPH
Research & Publications
Biography
Research Summary
While antibiotic decisions are made under uncertainty, a (near) ground truth becomes available several days later when cultures result. These unique features and challenges are well suited to decision-analytic modeling. I use a variety of modeling techniques including deterministic, compartmental, and machine learning models to develop heuristics for antibiotic selection.
Extensive Research Description
Current projects:
- Decision Analytic Model Comparing Azithromycin with Doxycycline for the Treatment of Chlamydia Infections in Emergency Department Patients
- Epidemiology of Emergency Department Patients with Sexually Transmitted Infections
- Improving and Standardizing Care for Survivors of Sexual Assault in the Emergency Medical System
- Cost-Effectiveness Analysis of Empiric Treatment Strategies for Urinary Tract Infections in the Emergency Department Setting
- Modeling ED patient flow and hospital crowding
Prior projects:
- Assessment of SOFA Score for Mortality Prediction in Patients with COVID-19
- Treatment of sodium disorders in ICU patients
Coauthors
Research Interests
Economics; Emergency Medicine; Emergency Treatment; Epidemiology; Urinary Tract Infections; Economics, Pharmaceutical; Informatics; Disaster Medicine; Evidence-Based Emergency Medicine; Policy; Inappropriate Prescribing; Clinical Decision-Making; Data Science; Cost-Effectiveness Analysis
Public Health Interests
Antimicrobial Resistance; Clinical Guidelines; Epidemiology Methods; Health Economics; Health Policy; Infectious Diseases; Modeling; Sexually-Transmitted Infections; Health Equity, Disparities, Social Determinants and Justice
Selected Publications
- 275 Factors Associated With Conversion to Procedural Sedation After Intra-articular Lidocaine Administration for Emergency Department Anterior Shoulder Dislocation ReductionWright D, Sherak R, Seo L, Parhar A, Baloescu C. 275 Factors Associated With Conversion to Procedural Sedation After Intra-articular Lidocaine Administration for Emergency Department Anterior Shoulder Dislocation Reduction. Annals Of Emergency Medicine 2023, 82: s122. DOI: 10.1016/j.annemergmed.2023.08.299.
- Yale Emergency Scholars (YES) Program: A model for expanding emergency medicine research capacityYang D, Panthagani K, Ryus C, Nelson A, Wright D, Sherak R, Bernstein S, D'Onofrio G. Yale Emergency Scholars (YES) Program: A model for expanding emergency medicine research capacity. Academic Emergency Medicine 2023, 30: 1179-1182. PMID: 37436420, DOI: 10.1111/acem.14777.
- Effects of correction rate for severe hyponatremia in the intensive care unit on patient outcomes.Kinoshita T, Mlodzinski E, Xiao Q, Sherak R, Raines NH, Celi LA. Effects of correction rate for severe hyponatremia in the intensive care unit on patient outcomes. J Crit Care 2023, 77: 154325. PMID: 37187000, DOI: 10.1016/j.jcrc.2023.154325.
- Association Between ICU-Acquired Hypernatremia and In-Hospital Mortality: Data From the Medical Information Mart for Intensive Care III and the Electronic ICU Collaborative Research Database.Olsen MH, Møller M, Romano S, Andersson J, Mlodzinski E, Raines NH, Sherak R, Jeppesen AN. Association Between ICU-Acquired Hypernatremia and In-Hospital Mortality: Data From the Medical Information Mart for Intensive Care III and the Electronic ICU Collaborative Research Database. Critical Care Explorations 2020, 2: e0304. PMID: 33354677, PMCID: PMC7746205, DOI: 10.1097/CCE.0000000000000304.
- Disaster Metrics: Evaluation of de Boer's Disaster Severity Scale (DSS) Applied to EarthquakesBayram JD, Zuabi S, McCord CM, Sherak RA, Hsu EB, Kelen GD. Disaster Metrics: Evaluation of de Boer's Disaster Severity Scale (DSS) Applied to Earthquakes. Prehospital And Disaster Medicine 2014, 30: 22-27. PMID: 25544545, DOI: 10.1017/s1049023x14001393.