Angus Clark Nairn, PhD

Charles B. G. Murphy Professor of Psychiatry

Departments & Organizations

Interdepartmental Neuroscience Program

Neuroscience Microarray Center, Yale

NIDA Neuroproteomics Center

Office of Student Research

Pharmacology: Neuropharmacology | Secondary Faculty

Psychiatry: Alzheimer's Disease Research Center (ADRC) | Connecticut Mental Health Center | Molecular Psychiatry, Division of | Specialized Center of Research (SCOR) to Develop Gender-Sensitive Treatment for Tobacco Dependence | Stress & Addiction Clinical Research Program

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Medicine, Pharmacology, and Physiology: Neurobiology, Neural Networks and Neuropharmacology; Receptors and Signal Transduction | Neuroscience: Drug Abuse; Molecular/Cellular Neuroscience; Neural Disorders; Neuropharmacology


Angus Nairn did his undergraduate training in biochemistry at the University of Edinburgh, Scotland and his PhD in muscle biochemistry in the laboratory of Professor Sam Perry at Birmingham University, England. He then carried out postdoctoral research in molecular neuroscience with Professor Paul Greengard at Yale, and moved with Professor Greengard to Rockefeller University in 1983 as a faculty member. He moved back to Yale University in 2001, where he is currently the Charles B.G. Murphy Professor of Psychiatry. He also holds a joint appointment in the Department of Pharmacology and is co-director of the Yale/National Institute of Drug Abuse Neuroproteomics Center at the Yale School of Medicine.

Education & Training

PhD University of Birmingham (1979)
Postdoctoral Fellow Yale University

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Contact Info

Angus Clark Nairn, PhD
Mailing Address
300 George St
New Haven, CT 06511-
Research Image 1

Beyond the Dopamine Receptor: Regulation and Roles of Serine/Threonine Protein Phosphatases: Left Panels: DARPP-32 (left, saggital section, positive immunoreactivity black), RCS (middle, coronal section, positive immunoreactivity white; caudate/putamen (CP) and nucleus accumbens (A); inset at right shows RCS enrichment in nucleus accumbens (left of dashed line) in more rostral section, ARPP-16 (right, saggital section, immunoreactivity white). Simple domain diagrams of each protein with their amino acid number and site of PKA phosphorylation are shown below the respective immunolocalization panels. Right Panel: Interactive roles of DARPP-32, RCS and ARPP-16 in regulation of signal transduction in striatal neurons.